Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer AssociationHumansMiceHistonesAnimalsStomach Neoplasms
Histone H4K8 lactylation modulated immunosuppressive properties by promoting FAP transcription and ECM remodeling.
Chao Huang, Ting Liu, Yuanyuan Zhao, Mei Wang, Deqiang Wang, Bo Shen, Wei Zhu, Li Sun
Published: 202610.1007/s10120-025-01685-9
Abstract
BACKGROUND & AIMS: The role of histone lysine lactylation (Kla) in gastric cancer mesenchymal stromal cells (GCMSCs) remains elusive. This study aimed to investigate the potential lactyltransferase and the influence of histone Kla in GCMSCs. METHODS:…
Preview only. Read the full abstract at the source