Journal of molecular modelingVascular Endothelial Growth Factor Receptor-2Molecular Docking SimulationMolecular Dynamics SimulationHumansPeptides
An in silico approach to peptide-based dual-receptor targeting for IL13RA2 and VEGFR-2 extracellular domain.
Saisha Islam, Liana R Cutter, Mary A Biggs, Sophia A Frantzeskos, Ipsita A Banerjee
Published: 202610.1007/s00894-025-06586-3
Abstract
CONTEXT: Vascular endothelial growth factor receptor-2 (VEGFR-2) and interleukin 13 receptor subunit-2 (IL13Rα2) are major drug targets due to their overexpression in several cancers that lead to tumor cell proliferation, metastasis, and poor prognos…
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