Mikrochimica actaBiosensing Techniquesbeta-ThalassemiaCRISPR-Cas SystemsAnimalsSpectrum Analysis
CRISPR/Cas12a-SERS biosensor based on sea urchin-like AuNPs for the detection of β-thalassemia mutant gene CD31.
Huaqiu Xu, Huagan Chen, Yixing Li, Yue Wang, Huihui Zeng, Ziyu Xu, Tingsha Chen, Delan Kong, Wenyi Huang, Hao Cheng, Haibo Zhou, Xudong Jiang, Jun Feng
Published: 202510.1007/s00604-025-07642-8
Abstract
Beta-thalassemia is a single-gene recessive disorder caused by mutations in the HBB gene, and approximately 1.5% of the global population are carriers of β-thalassemia. It is therefore vital to establish a rapid and sensitive method to detect the mut…
Preview only. Read the full abstract at the source