Journal of gastroenterology
Predictive factors for primary nonresponse to biologics in ulcerative colitis: a prospective multicenter study.
Atsushi Yoshida, Tomohisa Takagi, Kousaku Kawashima, Kei Moriya, Shigeki Bamba, Shintaro Sagami, Tomoyuki Hayashi, Motoki Kaneko, Takeo Naito, Shuji Kanmura, Kohei Asaeda, Shunji Ishihara, Shinsaku Nagamatsu, Yutaka Endo, Fumiaki Ueno
Published: 202510.1007/s00535-025-02313-0
Abstract
BACKGROUND: We sought to evaluate the predictive value of protease-3 (PR3)-anti-neutrophil cytoplasmic antibodies (ANCAs) and myeloperoxidase (MPO)-ANCA for primary nonresponse (PNR) to biologic agents in patients with ulcerative colitis (UC). METHOD…
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