Journal of gastroenterologyAnimalsMiceDietHigh-FatUp-Regulation
GPAM upregulation enhances hepatic fat deposition and reduces visceral adipose tissue in response to trans-fatty acids.
Teruki Miyake, Osamu Yoshida, Shinya Furukawa, Yusuke Sato, Yoshimasa Murakami, Ayumi Kanamoto, Masumi Miyazaki, Akihito Shiomi, Hironobu Nakaguchi, Mitsuhito Koizumi, Takao Watanabe, Yoshio Tokumoto, Masashi Hirooka, Masanori Abe, Bunzo Matsuura
Published: 202510.1007/s00535-025-02297-x
Abstract
BACKGROUND: Dietary fatty acids are involved in the pathogenesis of metabolic dysfunction-associated steatotic liver disease (MASLD). We examined the mechanism by which dietary fatty acid composition affects MASLD pathogenesis. METHODS: The MASLD mou…
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