Supportive care in cancer : official journal of the Multinational Association of Supportive Care in CancerHumansRetrospective StudiesMaleFemaleBisphosphonate-Associated Osteonecrosis of the Jaw
Efficacy and risks of drug holiday in the management of medication-related osteonecrosis of the jaw in cancer patients: a single-center retrospective study.
Hironobu Hata, Kenji Imamachi, Kazuhito Yoshikawa, Mayumi Kamaguchi, Toshihisa Osanai, Masashi Matsuzaka, Kenichi Watanabe, Nobumoto Tomioka, Toru Harabayashi, Katsuya Fujimoto, Satoshi Oizumi, Michihiro Ueda, Hiroaki Hiraga, Ikuya Miyamoto
Published: 202610.1007/s00520-026-10346-1
Abstract
PURPOSE: Discontinuing bone-modifying agents (BMAs) during management of medication-related osteonecrosis of the jaw (MRONJ) remains controversial. This retrospective study evaluates the impact and potential risks of BMA drug holidays in cancer patie…
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