Surgical endoscopyHumansRectal NeoplasmsRandomized Controlled Trials as TopicNeoadjuvant TherapyAdenocarcinoma
Is radical surgery always necessary in early rectal cancer? A systematic review of randomised trials.
Rathin Gosavi, Thang Chien Nguyen, Stephen Bell, Paul McMurrick, William Teoh, Vignesh Narasimhan
Published: 202610.1007/s00464-025-12431-8
Abstract
BACKGROUND: Total mesorectal excision (TME) remains the standard of care for operable rectal cancer but is associated with significant long-term morbidity. Local excision (LE) following neoadjuvant therapy offers a potential organ-preserving alternat…
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