Cell and tissue researchConnexinsHumansDrug DiscoveryNerve Tissue ProteinsAnimals
Panx1 and drug discovery: from non-specific inhibitors to tailored drug compounds.
Michael Kohr, Carola Meier
Published: 202610.1007/s00441-025-04038-1
Abstract
Pannexin (Panx)-1-mediated ATP release has been associated with a broad range of pathological conditions. Conversely, the use of Panx1-inhibitors has shown promising results in the medication of diseases, such as neuroinflammation, melanoma and epile…
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