Virchows Archiv : an international journal of pathology
Endometrial carcinomas with solid basaloid morphology and geographic necrosis: clinicopathological and molecular features of 18 cases.
Mengyuan Cai, Tian Tang, Rui Bi, Huijuan Ge, Xiaoyu Tu, Ke Zuo, Ziling Huang, Xiaoyan Zhou, Wentao Yang
Published: 202510.1007/s00428-025-04367-0
Abstract
Pilomatrix-like high-grade endometrioid carcinoma (PiMHEC) is characterized by solid basaloid morphology, geographic necrosis, and shadow cells, often associated with CTNNB1 mutations and aberrant β-catenin expression, exhibiting aggressive behavior.…
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