Virchows Archiv : an international journal of pathology
Molecular co-alteration patterns of RICTOR-mutant metastatic lung adenocarcinomas: a single-center cohort study.
Mehmet Berkay Ozata, Ali Aytac, Ibrahim Halil Erdogdu, Ali Alkan, Ozgur Tanriverdi
Published: 202510.1007/s00428-025-04329-6
Abstract
RICTOR, a core component of the mTORC2 complex, regulates AKT signaling and has been implicated in tumor biology. While RICTOR amplification and overexpression have been reported, the mutational landscape of RICTOR and its molecular context in non-sm…
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