Histochemistry and cell biologyAnimalsAstrocytesMicrogliaMiceInflammation
Acute systemic inflammation induces region-specific morphological remodeling of astrocytes and microglia concurrent with depression-like behavior.
An-Qi Zhang, Meng-Meng Zhang, Ling-Jie Li, Mei-Xue Yuan, Rong-Yu Liu, Peng Chen, Chen-Wei Wang, Yu Wang, Jiang-Ning Zhou, Qing-Hong Shan, Xin-Ya Qin
Published: 202510.1007/s00418-025-02440-y
Abstract
Neuroinflammation is recognized as a key mechanism underlying depression, with glial cells playing a central role in regulating neuronal activity and neuroimmune interactions. However, how microglia and astrocytes in distinct brain regions respond mo…
Preview only. Read the full abstract at the source