Histochemistry and cell biologyHumansImmunohistochemistrySoftwareAlgorithmsImage Processing
A comparison of pixel intensity-based and object-based image analysis software algorithms for assessing immunohistochemical staining of sections from paraffin-embedded human tumor samples.
Sarah E Kimambo, Josh Overton, Nicole A Bouffard, Kyra Lee, Abiy Ambaye, Douglas J Taatjes
Published: 202510.1007/s00418-025-02430-0
Abstract
Histopathological diagnosis relies on careful and expert assessment of tissue as guided by multiple criteria relevant to specific immunohistochemical (IHC) markers. Computer-aided detection or diagnosis systems have recently been deployed to detect a…
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