Journal of neurologyHumansFemaleMaleTomographyOptical Coherence
Retinal nerve fiber layer thinning in multiple sclerosis: clinical implications, cognitive associations, and effects of disease-modifying therapies.
Hongmei Tan, Zegang Yin, Jingzi Zhangbao, Xiang Li, Yuxin Li, Fanru He, Yiqin Xiao, Haiqing Li, Liqin Yang, Chongbo Zhao, Lei Zhou, Chao Quan
Published: 202510.1007/s00415-025-13565-4
Abstract
BACKGROUND: Peripapillary retinal nerve fiber layer (pRNFL) thinning, detected by optical coherence tomography (OCT), is an early marker of neuroaxonal injury in multiple sclerosis (MS). Its prognostic value for long-term outcomes and responsiveness…
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