European archives of psychiatry and clinical neuroscience
Choroid plexus alterations in long COVID and their associations with IL-6.
Yuan Cao, Paulo Lizano, Alejandra P Garza, Ildiko Rita Dunay, Xiaoqin Zhou, Philipp A Reuken, Andreas Stallmach, Martin Walter, Meng Li, Bianca Besteher
Published: 202610.1007/s00406-025-02177-8
Abstract
SARS-CoV-2 disrupts the choroid plexus (ChP) epithelium by binding to the ACE-2 receptor, causing blood cerebrospinal fluid barrier leakage and permitting interleukin (IL)-6 and pathogens into the brain, subsequently leading to demyelination, white m…
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