Mammalian genome : official journal of the International Mammalian Genome SocietyHypopituitarismHumansGenome-Wide Association StudyQuantitative Trait LociMendelian Randomization Analysis
Exploring the mediating role of potential therapeutic genes in the pathogenesis of hypopituitarism through the metabolites from a genomic perspective.
Yesheng Sun, Ying Zhang, Tengfei Luan, Ruichun Li, Dongpeng Cai, Wei Zhang
Published: 202510.1007/s00335-025-10169-1
Abstract
Hypopituitarism is a severe endocrine disorder characterized by a partial or complete hormone deficiency in the anterior or posterior pituitary gland. Current treatment relies on hormone replacement therapy, which is unable to mimic normal physiologi…
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