Mammalian genome : official journal of the International Mammalian Genome SocietyHumansCarcinomaHepatocellularLiver NeoplasmsPrognosis
Multi-omics dissection of RAD21-PON1 axis reveals metabolic-immune crosstalk and prognostic significance in hepatocellular carcinoma.
Zhe Liu, Fang Liu, Zhongyu Yao, Yun Long, Nanjun Chen, Jixiang Yu, Lei Wang, Yang Wang, Ka-Chun Wong
Published: 202510.1007/s00335-025-10166-4
Abstract
RAD21, a key cohesin subunit, participates in chromatin regulation and may influence tumor metabolism and immunity. Its role in liver HCC remains unclear. We investigated whether RAD21 regulates PON1 and how this axis integrates metabolic and immune…
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