Mammalian genome : official journal of the International Mammalian Genome SocietyHumansPulmonary DiseaseChronic ObstructiveMacrophagesAlveolar
Impaired immune metabolism in COPD driven by dysfunction of CXCL16 + alveolar macrophages: multivariate causal evidence.
Xianqiang Zhou, Yixin Zhang, Jie Yang, Zhengjie Jin, Zhancheng Gao, Cuiling Feng
Published: 202510.1007/s00335-025-10163-7
Abstract
Chronic obstructive pulmonary disease (COPD) is a leading global cause of mortality, with alveolar macrophages (AMs) dysfunction implicated in pathogenesis, though key molecular drivers remain unclear. This study integrated multi-omics approaches to…
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