European radiology
Optimizing whole-body MRI for early cancer detection in Li-Fraumeni syndrome: a prospective bicentric study.
Myriam Margareta Keymling, Felix Tobias Kurz, Tristan Anselm Kuder, Sebastian Bickelhaupt, Thomas Hielscher, Robert Hog, Theresa Mokry, Tawfik Moher Alsady, Sarah Schott, Christian Kratz, Diane Miriam Renz, Heinz-Peter Schlemmer
Published: 202510.1007/s00330-025-11880-y
Abstract
OBJECTIVES: Annual whole-body MRI (WB-MRI) is recommended for early cancer detection in individuals with Li-Fraumeni syndrome (LFS). However, there is no agreement on a standardized MRI protocol. This study evaluated the diagnostic performance of dif…
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