Current microbiologyHumansTalaromycesCTLA-4 AntigenB7-2 AntigenJurkat Cells
The Role of Talaromyces Marneffei Binding To CD86 in the CD86-CTLA4 Regulatory Pathway.
Shangrong Tang, Krishna Hamal, Yongjun Meng, Meilan Xu, Donghua Liu
Published: 202510.1007/s00284-025-04687-z
Abstract
Talaromyces marneffei (TM), an opportunistic pathogenic fungus, binds to CD86, which acts as a co-stimulatory molecule for CTLA4. CD86 activates CTLA4, which transmits inhibitory signals, yet its role in TM immune responses remains unclear. In this s…
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