European journal of nuclear medicine and molecular imaging
Molecular imaging of fibroblast activation in systemic sclerosis using [18F]AlF-NOTA-FAPI-04 PET/CT: a prospective cohort study.
Meixin Zhao, Hui Wei, Meng Wang, Zeyang Wang, Xinwei Li, Hui Li, Annan Zhang, Song Xue, Marcus Hacker, Weifang Zhang, Rong Mu, Xiang Li
Published: 202510.1007/s00259-025-07586-4
Abstract
PURPOSE: This prospective cohort study evaluated the utility of [¹⁸F]AlF-NOTA-FAPI-04 PET/CT for whole-body assessment of fibroblast activation in systemic sclerosis (SSc), correlating organ-specific uptake with clinical indicators of severity and mu…
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