European journal of nuclear medicine and molecular imaging
NHOC/NHOP as novel biomarkers for predicting lymph node metastasis in NSCLC using PET/CT radiomics and machine learning: a two-center retrospective study.
Qianyi Huang, Junjian Mo, Xuanbang Deng, Yongluo Jiang, Min Yang, Guojie Wang, Xiao Yang, Jie Yu, Wei Fan, Ying Wang
Published: 202510.1007/s00259-025-07560-0
Abstract
PURPOSE: NHOC and NHOP, defined as the normalized distances from peak uptake to tumour centroid and perimeter, are novel PET/CT metrics of tumour aggressiveness. This two-centre study assessed the baseline NHOC/NHOP for predicting lymph node metastas…
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