Pediatric radiologyHumansHypoxia-IschemiaBrainInfantNewborn
Multi-pool chemical exchange saturation transfer magnetic resonance imaging as a molecular-specific biomarker: detecting histopathological changes in neonatal hypoxic-ischemic encephalopathy.
Xiamei Zhuang, Yupeng Wu, Guihua Jiang, Ke Jin, Jianqi Li, Junwei Li, Meitao Liu, Yanfang Wu, Huiting Zhang, Huashan Lin
Published: 202610.1007/s00247-025-06417-w
Abstract
BACKGROUND: Neonatal hypoxic-ischemic encephalopathy (HIE) diagnosis is confounded by heterogeneous neural injury and metabolic dysfunction. Multi-pool chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) uniquely quantifies…
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