Analytical and bioanalytical chemistry
A multiplex method for high-throughput quantification of conjugated saccharide in glycoconjugate vaccines.
Giovanni Santostefano, Alessio Corrado, Carmine Malzone, Leonardo Mori, Diego Amendola, Stefania Berti, Valeria Di Bussolo, Riccardo De Ricco
Published: 202510.1007/s00216-025-06249-5
Abstract
Glycoconjugate vaccines rely on the accurate quantification of its active ingredient, also called conjugated saccharides (CS), which is usually estimated from the indirect measurement of total and free (unconjugated) saccharide to ensure product qual…
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