Psychopharmacology
Activation of infralimbic cortex neurons projecting to the nucleus accumbens shell suppresses discriminative stimulus-triggered relapse to cocaine seeking in rats.
Hajer E Algallal, Isabel Laplante, Domiziana Casale, Shaghayegh Najafipashaki, Audrey Pomerleau, Thomas Paquette, Anne-Noël Samaha
Published: 202510.1007/s00213-025-06985-7
Abstract
RATIONALE: Cocaine addiction is marked by high relapse rates, often triggered by drug-associated cues in the environment. These can be conditioned stimuli (CSs), which occur after drug intake and signal drug delivery, and discriminative stimuli (DSs)…
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