Psychopharmacology
Histone deacetylase inhibitor sodium butyrate increases risk-taking during acquisition of the rat gambling task.
Kelly M Hrelja, Stephanie Hipkin, Brett A Hathaway, Varshi Domah, Chloe S Chernoff, Catharine A Winstanley
Published: 202510.1007/s00213-025-06937-1
Abstract
RATIONALE: Pairing casino-inspired audiovisual cues with reward delivery significantly increases risky decision-making in laboratory-based gambling tasks across rats and humans. The neurocognitive mechanisms underlying this effect are unclear. Data f…
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