Psychopharmacology
History of episodic heavy alcohol use predicts antidepressant effectiveness of ketamine.
Aaishah R Raquib, Vy Nguyen, Joshua C Brown, Amanda E Sedgewick, Stephen Seiner, Joseph J Taylor, Shan H Siddiqi, Robert C Meisner
Published: 202510.1007/s00213-025-06918-4
Abstract
RATIONALE: Antidepressant response to ketamine is greatest in patients with a family history of alcohol use disorder (AUD), but it remains unclear if this trend holds true for a personal history of alcohol use. OBJECTIVE: We hypothesized that a perso…
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