Naunyn-Schmiedeberg's archives of pharmacology
Asiaticoside protects against PDF-induced peritoneal fibrosis via suppression of AhR/Nrf2-mediated MMT and oxidative stress.
Junyi Zhao, Wen Zhou, Wenxuan Xue, Mengyun Yuan, Mengya Wang, Zhichen Cai, Ning Ding
Published: 202510.1007/s00210-025-04927-w
Abstract
Peritoneal fibrosis (PF) is a major complication of long-term peritoneal dialysis (PD). This study investigated the protective effects and mechanisms of asiaticoside (AC) against PF. In vitro, HMrSV5 cells were exposed to peritoneal dialysis fluid (P…
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