Naunyn-Schmiedeberg's archives of pharmacology
Targeting STAT3 by SH-4-54 suppresses the occurrence and inactivates oxidative phosphorylation in small-cell lung cancer via the SRC signaling.
Chen Chen, Hang Hu, Zhongxiang Liu, Yongqian Jiang, Minhua Shi
Published: 202610.1007/s00210-025-04893-3
Abstract
Small-cell lung cancer (SCLC) and non-small-cell lung cancer (NSCLC) are the two main types of lung cancer. Signal transducer and activator of transcription 3 (STAT3) plays an oncogenic role in various malignancies, including lung cancer, and targeti…
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