Naunyn-Schmiedeberg's archives of pharmacology
Nose to brain delivery of dapoxetine-loaded PLGA nanoparticle for treatment of premature ejaculation distress in normal and diabetic rats with in silico targeting brain FOX and serotonin proteins.
Fatma I Abo El-Ela, Heba F Salem, Mohamed M Nafady, Rasha M Kharshoum, Hanan O Farouk
Published: 202510.1007/s00210-025-04876-4
Abstract
Psychological and emotional sexual conditions in men include premature ejaculation. Premature Ejaculation (PE) has 4%-66% worldwide effects on self-esteem, relationships, and quality of life. Poor sexual confidence, anxiety, and sadness may worsen th…
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