Naunyn-Schmiedeberg's archives of pharmacology
Evaluation of 1H-pyrazol-1-yl benzenesulfonamide derivatives in alleviating inflammatory bowel disease via PI3K/Akt/mTOR signaling pathway in zebrafish models.
S P Ramya Ranjan Nayak, D Priya, V Chitra, Ajay Guru, Mohamed Farouk Elsadek, Mohamed S Elshikh, Selvaraj Arokiyaraj, M K Kathiravan, Jesu Arockiaraj
Published: 202510.1007/s00210-025-04807-3
Abstract
The incidence of inflammatory bowel disease (IBD) is increasing in developed nations, leading to a significant increase in healthcare expenses. It is characterized by chronic intestinal inflammation driven by excessive oxidative stress and dysregulat…
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