Naunyn-Schmiedeberg's archives of pharmacology
Targeting centromere protein M represses cell growth and mobility via inactivating AKT pathway but less affects BRAF inhibitor sensitivity in cutaneous melanoma.
Shujie Ruan, Zhechen Zhu, Binlin Luo, Youzhi Tang, Wei Yan, Jingping Shi
Published: 202510.1007/s00210-025-04791-8
Abstract
Centromere protein M (CENPM) promotes oncogenesis and serves as a prognostic biomarker in some cancers, but its implication in cutaneous melanoma is not clear. This study aimed to investigate the effect of targeting CENPM on cell proliferation, colon…
Preview only. Read the full abstract at the source