Naunyn-Schmiedeberg's archives of pharmacology
Lactobacillus rhamnosus regulates airway epithelial cell senescence through the ADCK5/PI3K/AKT signaling axis and alleviates airway inflammation in asthma.
Peiqin Zhu, Tong Yang, Hanting Ye, Li Tan, Junyang Wang, Zihan Yang, Wei Mao
Published: 202510.1007/s00210-025-04781-w
Abstract
Lactobacillus rhamnosus (LGG) can alleviate ovalbumin (OVA)-induced asthma, but whether its mechanism of action involves cell senescence is unknown. OVA was used to establish a mouse model of asthma. LGG was administered by oral gavage, and a lentivi…
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