Naunyn-Schmiedeberg's archives of pharmacology
Gastrodin alleviates loperamide-induced slow transit constipation in mice by modulating the MAPK signaling pathway.
Xinyu Ge, Bozhao Wu, Xiaohui Dou, Mingchen Sun, Ji-Ao Wu, Daqing Sun
Published: 202510.1007/s00210-025-04763-y
Abstract
BACKGROUND: Slow transit constipation (STC) is a prevalent functional gastrointestinal disorder. Gastrodin (GAS), a natural compound, has demonstrated protective effects in intestinal contexts; however, its therapeutic potential and mechanisms of act…
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