Naunyn-Schmiedeberg's archives of pharmacology
Methyl rosmarinate alleviates myocardial ischemia-reperfusion injury in mice via triggering TGR5/AMPK signaling axis.
Weimin Zhou, Jing Qiu, Meng Peng, Yuting Liu, Chunguang Qiu, Liang Pan
Published: 202510.1007/s00210-025-04703-w
Abstract
The key mechanism of myocardial ischemia-reperfusion injury (MIRI) is the oxidation reaction, and methyl rosmarinate (MR) has a strong antioxidant effect, but its role in MIRI has not been reported. About 3 weeks after tail vein injection of AV-TGR5…
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