Mechanistic insights into piperlongumine's neuroprotective role against cisplatin-induced neuropathy: a network pharmacology, molecular dynamics, and experimental approach.

This study aimed to evaluate the neuroprotective effect of piperlongumine (PL), a natural alkaloid, on cisplatin-induced peripheral neuropathy (CIPN) in a mouse model, and to elucidate the possible underlying mechanisms involved in its action. In our…

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