Naunyn-Schmiedeberg's archives of pharmacology
Associations of sphingosine-1-phosphate with soluble P-selectin and adverse clinical outcome in patients with cerebral ischemia with and without acetylsalicylic acid treatment.
Nils-Ole Gloyer, Eileen Moritz, Laura Schwieren, Ulrike Meyer, Götz Thomalla, Günter Daum, Tim Magnus, Rainer Böger, Chi-Un Choe, Bernhard H Rauch, Edzard Schwedhelm
Published: 202510.1007/s00210-025-04595-w
Abstract
Patients with overt cerebral ischemia are at risk for adverse events after hospital discharge. Sphingosine-1-phosphate is a potent lipid mediator produced and secreted by platelets, which is inhibited via acetylsalicylic acid (ASA). The associations…
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