Archives of toxicology
Dimethyltryptamine and harmine, components of ayahuasca, prevented cocaine-induced apoptosis in SH-SY5Y human neuroblastoma cells.
Gabriela Salles, Carolina Aparecida de Faria Almeida, Isabella de Carvalho Alves, Giulia de Assis Braz, Flávia Barrio Lopes, João Paulo Dos Santos Fernandes, Daniela Aparecida Chagas-Paula, Albert Katchborian-Neto, Matheus Fernandes Alves, Vitor Bruno, Beatriz Aparecida Passos Bismara Paranhos, Tania Marcourakis, Larissa Helena Lobo Torres, Raphael Caio Tamborelli Garcia
Published: 202510.1007/s00204-025-04208-8
Abstract
Ayahuasca is a psychoactive brew traditionally used in religious rituals by indigenous Amazonian populations and South American syncretic religions such as Santo Daime and União do Vegetal. Its psychoactive effects are primarily due to N,N-dimethyltr…
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