Diabetologia
Identification of a genetic risk factor for metformin-induced vitamin B12 deficiency.
Faye D Baldwin, Khaled F Bedair, Andrea L Jorgensen, Lewis Green, Innocent G Asiimwe, Colin N A Palmer, Archie Campbell, Caroline Hayward, Qing Pan, Shiyu Shu, Josephine H Li, Diabetes Prevention Program (DPP) Research Group, Ewan R Pearson, Munir Pirmohamed, Daniel F Carr
Published: 202610.1007/s00125-025-06655-5
Abstract
AIMS/HYPOTHESIS: Metformin, a mainstay of treatment for type 2 diabetes, can cause vitamin B12 deficiency. Clinical risk factors have been identified but genetic factors remain undiscovered. Our objective was to identify and validate genetic predispo…
Preview only. Read the full abstract at the source