Diabetologia
Transient ER stress cell-autonomously promotes beta cell cycling in mice.
Stephanie Bourgeois, Annelore Van Mulders, Yves Heremans, Gunter Leuckx, Lien Willems, Sophie Coenen, Laure Degroote, Julie Pierreux, Daliya Kancheva, Isabelle Scheyltjens, Kiavash Movahedi, Françoise Carlotti, Eelco de Koning, Xiaoyan Yi, Chiara Vinci
Published: 202610.1007/s00125-025-06649-3
Abstract
AIMS/HYPOTHESIS: Regenerating endogenous pancreatic beta cells is a potentially curative yet currently elusive strategy for diabetes therapy. Mimicking the microenvironment of the developing pancreas and leveraging vascular signals that support pancr…
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