Diabetologia
Diabetogenic processes for insulin resistance-linked hyperinsulinaemia are associated with colorectal cancer.
Xuan Zhou, Magdalena Sevilla-Gonzalez, Amanda I Phipps, Miriam Udler, Sergi Castellví-Bel, Andrew T Chan, Andrew J Pellatt, Robert E Schoen, Edward Giovannucci, Marc J Gunter, Jose C Florez, Ulrike Peters, Mingyang Song, Jordi Merino
Published: 202510.1007/s00125-025-06631-z
Abstract
AIMS/HYPOTHESIS: Type 2 diabetes has been associated with increased risk of colorectal cancer (CRC), but the specific diabetogenic pathways contributing to this risk remain unclear. METHODS: We analysed individual-level data from 129,420 participants…
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