Cellular and molecular life sciences : CMLS
Host E3 ligase RNF2 restricts African swine fever virus replication through targeting viral pA104R for its K5 site ubiquitination degradation.
Zhonghui Zhang, Jifei Yang, Zhancheng Tian, Hualin Sun, Xiaoqiang Zhang, Jianhao Zhong, Songlin Yang, Yikang Chen, Jianxun Luo, Hong Yin, Guiquan Guan, Qingli Niu
Published: 202610.1007/s00018-026-06085-5
Abstract
The African swine fever virus (ASFV) -encoded late structural protein pA104R is a putative histone-like protein, which is also a DNA-binding related protein required for ASFV DNA replication, transcription, and genome packaging. However, the molecula…
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