Cellular and molecular life sciences : CMLS
SNX-3 confers lysosomal fusion-competence to sustain basal autophagy.
Qiaoju Kang, Zhenyu Liu, Lianyan Xiang, Sai Yang, Ping Yi, Rongying Zhang
Published: 202610.1007/s00018-025-06074-0
Abstract
Autophagy, the process for recycling cytoplasm in the lysosome, relies on tightly regulated membrane trafficking. During autophagy, autophagosomes either fuse with endosomes generating amphisomes and then lysosomes, or directly fuse with lysosomes, i…
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