Inflammation research : official journal of the European Histamine Research Society ... [et al.]AnimalsBlood-Brain BarrierCytokinesMaleRecombinant Proteins
Recombinant TsP53 mitigates inflammation and blood-brain barrier disruption in CLP-induced septic mice.
Deng Zhezhi, Sun Zaiyuan, Lu Gengxin, Gong Wenqian, Guo Jifeng, Guo Li, Wei Lingyu, Xu Jia
Published: 202610.1007/s00011-025-02148-8
Abstract
BACKGROUND: Sepsis-associated encephalopathy (SAE), a neurological complication of sepsis without direct CNS infection, currently lacks established pharmacological therapy. Key pathological features include excessive microglial activation and blood-b…
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