Inflammation research : official journal of the European Histamine Research Society ... [et al.]SepsisReceptorsImmunologicMacrophagesHumans
The SPI1/LILRB2 axis modulates macrophage tolerance via crosstalk with TLR8 signaling: implications for sepsis immunotherapy.
DuJiang Yang, Zhijun Ye, Junjie Chen, Shuang Wang, Jiexiang Yang, GuoYou Wang
Published: 202510.1007/s00011-025-02125-1
Abstract
The study by Bai and Guo (Biol Direct 20(1):73. https://doi.org/10.1186/s13062-025-00669-0 , 2025) offers significant insights into the molecular mechanisms of LPS tolerance in macrophages. The authors identify a novel pathway wherein the transcripti…
Preview only. Read the full abstract at the source