Advances in experimental medicine and biologyLigand-Gated Ion ChannelsHumansAnimalsStructure-Activity RelationshipIon Channel Gating
Structure-Function Studies of Pentameric Ligand-Gated Ion Channels: Combining Experimental and Computational Approaches.
Wayland W L Cheng, Mark J Arcario
Published: 202610.1007/978-3-032-07523-9_11
Abstract
Pentameric ligand-gated ion channels (pLGICs) are a family of cation- and anion-selective channels that mediate fast synaptic transmission and regulate excitability in the nervous system. They include the GABA(A) receptor, nicotinic acetylcholine rec…
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