Methods in molecular biology (Clifton, N.J.)High-Throughput Nucleotide SequencingHumansDNA Copy Number VariationsNucleic Acid Amplification TechniquesSequence Analysis
Assessing Amplification Quality and Bias in MDA Methods Through Comparative Analysis of Short-Read Sequencing.
E D Lozano-Escobar, V Mateo-Cáceres, C Mayoral-Campos, M Redrejo-Rodríguez
Published: 202610.1007/978-1-0716-5060-8_10
Abstract
Although high-throughput sequencing methods have greatly improved over the last few years, direct sequencing remains unfeasible when DNA quantity or quality is limited. In such instances, various whole genome or metagenome amplification (WGA) techniq…
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