Methods in molecular biology (Clifton, N.J.)AnimalsLeukocytesMononuclearHumansMice
Humanized Murine Model with Peripheral Blood Mononuclear Cells as a Strategy to Translate Experimental Biomedical Research.
Matheus R Gonçalves, Victor R M Costa, Jennifer R Martins, Viviane L Batista, Jéssica A B Pereira, Fernanda L Tana, Walison Nunes Silva, Pedro P G Guimarães, Barbara Maximino Rezende, Vanessa Pinho, Mauro Martins Teixeira, Jordana G A Coelho-Dos-Reis, Celso Martins Queiroz-Junior, Vivian V Costa
Published: 202610.1007/978-1-0716-5019-6_12
Abstract
One of the main limitations to developing new therapies for human diseases and understanding their pathogenicity mechanisms is difficulty to translate the results obtained in animal models to the clinic. Factors such as the existence of pathogens wit…
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