Methods in molecular biology (Clifton, N.J.)DNANucleic Acid ConformationSuperhelicalProtein Binding
Gel Electrophoresis Analysis of SMC-Mediated Effects on DNA Topology.
Joaquim Roca
Published: 202610.1007/978-1-0716-5005-9_7
Abstract
SMCs might alter the topology of interacting DNA as a result of two processes: stoichiometric binding and dynamic supercoiling. Stoichiometric effects refer to DNA deformations constrained at the DNA interaction sites. Dynamic effects are cumulative…
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