Methods in molecular biology (Clifton, N.J.)Optical TweezersMicroscopyFluorescenceDNACell Cycle Proteins
Visualizing Binding of Single SMC Complexes to DNA Substrates Using Combinational Optical Tweezers and Fluorescence Microscopy.
Anno I Koetje, Gemma L M Fisher, Menelaos Voulgaris, Sanjana Saravanan, Richard J Bartlett, Stephen J Cross, Luis Aragon
Published: 202610.1007/978-1-0716-5005-9_3
Abstract
Structural Maintenance of Chromosomes (SMC) complexes undertake a variety of DNA-centric processes to both organize and maintain genomes throughout the cell cycle. Their multiple DNA binding sites and conformational dynamics have made fully character…
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