Methods in molecular biology (Clifton, N.J.)HumansDystrophinRNA SplicingTranscriptionGenetic
Total RNA-seq as a Tool to Study DMD Splicing and Transcriptional Dynamics.
Diane M Dunn, Robert B Weiss
Published: 202610.1007/978-1-0716-4811-7_2
Abstract
Advances in RNA analysis of dystrophin (DMD) mutations have been significantly influenced by improvements in methods to study mRNA transcription and splicing. Early breakthroughs, such as the 1988 cDNA sequencing of the 14-kb muscle transcript isofor…
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